Some people follow a ketogenic diet seeking to lose weight, feel more energised, or gain control over their eating habits.
Others may turn to this diet in an effort to treat their epilepsy, bipolar disorder, or diabetes.
Regardless of their reasoning for adopting this eating pattern, a key question remains: can high LDL cholesterol levels on a ketogenic diet be safe?
In Episode #311, I’m joined by Dr William Cromwell, MD and Dave Feldman to explore this question.
:point_down: Visit The Proof website for the full show notes and supporting studies.
:point_down: https://theproof.com/podcast/ Dr William Cromwell is a lipidologist with over 35 years of clinical practice experience.
Since 1990, Dr Cromwell’s practice has specialised in managing lipid and lipoprotein disorders.
He has authored over two dozen peer-reviewed papers and book chapters on evaluating and managing lipoprotein disorders and lipoprotein analytics.
Dave Feldman is a software and platform engineer, an entrepreneur, and founder of the Citizen Science Foundation.
His life took a radical turn on seeing his cholesterol skyrocket after adopting a ketogenic diet, leading him to research lipidology.
Through a series of self-experiments and partnering with formal researchers, he has since published the "Lipid Energy Model" which may explain this phenomenon.
Connect with Dr William Cromwell: - Twitter/X (personal): /lipoprotein - Twitter/X (Precision Health Reports): / precisehlthrpt - LinkedIn (personal): /wcromwellmd - LinkedIn (Precision Health Reports): / precisionhealthreports - Facebook: / precisionhealthreports - Instagram: / precisehlthrpt - Website (personal): https://www.mylipid.com/ - Website (Precision Health Reports): https://precisionhealthreports.com/ Connect with Dave Feldman: - Twitter/X: / realdavefeldman - YouTube: / @realdavefeldman - Instagram: / realdavefeldman - Citizen Science Foundation: https://citizensciencefoundation.org/ - Own Your Labs: https://ownyourlabs.com/ - Cholesterol Code: https://cholesterolcode.com/ We covered: 00:00 Intro 01:54 Dr.
William Cromwell: Background as a Lipidologist and LDL Research 05:34 Dave Feldman's Ketogenic Diet and Elevated LDL Experience 12:30 Unpacking the Lipid Hypothesis and Cardiovascular Risk 20:40 The history and evolution of the lipid hypothesis 23:39 The role of apoB lipoproteins in atherosclerosis 31:59 Factors beyond apoB involved in atherosclerosis and mortality risk 41:43 The complexity of interpreting mortality data in the context of apoB 44:00 Macrophages and the process of atherosclerosis 52:57 Beyond ApoB: Metabolic Vulnerability, Inflammation and Mortality Risk 1:10:35 Transcytosis: A New Perspective on LDL Movement and Atherosclerosis 1:17:33 Exploring Low Cholesterol Impacts and Genetic Disorders 1:22:30 Macrophage Function and Phenotype Across Different ApoB Drivers 1:31:41 Defining Lean Mass Hyper Responders in the Context of a Ketogenic Diet 1:38:00 Investigating PCSK9 and Its Effects on Healthspan 1:44:18 Assessing cardiovascular risk in lean mass hyper-responders 2:02:19 Statin safety, adverse effects, and patient reluctance 2:11:10 Ketogenic Diets and Elevated LDL: Risks and Benefits in the Absence of Long-Term Data 2:18:40 Insulin Resistance, ApoB, and Cardiovascular Risk: Challenges in Assessment and Imaging 2:33:06 Lean Mass Hyper-Responder Study: Design, Recruitment, and Eligibility Criteria 3:05:15 Outro Enjoy, friends.
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Simon Hill, MSc, BSc (Hons) Creator of http://theproof.com/ and host of The Proof with Simon Hill https://theproof.com/podcast/ Author of The Proof is in the Plants https://theproof.com/book/
Over the years, celebrities have wielded incredible power in the world of endorsements . It was not until a long time later that there were great game lovers Uncovered this mysterious text President The members of Dark Dragon roared in grief and indignation. When a well-known figure puts their stamp of approval on a product or service, it can instantly boost its credibility and popularity . Now she is in a very excited and complicated mood. Xia Yu s help has moved this beautiful woman, and women can easily regard being moved as another kind of emotion, but anyway, Now Xinyuexin has no idea of continuing to lead the team, she decided to stay here to recruit new players. One such celebrity who has captured the attention of the public with her endorsements is media mogul Oprah Winfrey . It s time, now the auction starts Following Xiaolou s voice, the entire auction house was silent, no one raised the price, and everyone was waiting This piece of equipment Xia Mengyao looked at Xia Yu, because she saw the hot light in Xia Yu s eyes. Known for her influence and impact on popular culture, Oprah’s approval can turn a niche product into a household name.
Keto Gummies: The Latest Craze
In recent years, the ketogenic diet has gained popularity for its potential health benefits, including weight loss and improved mental clarity . As more people look for ways to incorporate keto-friendly foods and snacks into their daily routines, keto gummies have emerged as a popular choice . The man in black s voice was very soft, but it was clearly heard by everyone. These chewy treats offer a convenient and tasty way to satisfy cravings while staying within the guidelines of a low-carb, high-fat diet.
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One of the key advantages of keto gummies is their portability and ease of use . Tell me about it, Xia Mengyao asked. Therefore, Xin Yuexin cried and said that after Xia Mengyao disappeared, the news of them going to establish a trade union spread, which attracted the attention of the dark dragon. Unlike traditional keto snacks that require preparation or refrigeration, keto gummies can be easily carried in a purse or pocket for a quick and convenient energy boost . The old man knew that this was not a joke. Additionally, many keto gummies are sweetened with natural ingredients like stevia or erythritol, making them a guilt-free indulgence for those following a ketogenic lifestyle.
Another benefit of keto gummies is their versatility . Lin Feng smiled, and then ordered to the two women Now change into auspicious clothes immediately, and start training in five minutes Change now Here Shen Lanni widened eyes, obviously a little surprised. These chewy treats come in a variety of flavors, from fruity to savory, allowing consumers to satisfy their cravings without straying from their dietary goals . Now Zuo Butterfly realizes that everyone has made a very serious mistake, that is, this Chen Tianming can t kill him alone, and besides, he has so many subordinates who are so powerful in martial arts. Whether you prefer the tangy taste of lemon or the rich flavor of chocolate, there is a keto gummy option to suit every palate.
Oprah Winfrey: A Trusted Voice
As one of the most influential media figures of our time, Oprah Winfrey has built a reputation for promoting products and services that align with her values and principles . From books to beauty products, Oprah’s endorsements carry weight with consumers who trust her judgment and taste . Why Xia Yu was not angry, but he just didn t understand why he just agreed and said it was no good in a blink of an eye I m sorry, the great god doesn t allow me to do this the supernatural master job changer said apologetically, but his tone couldn t refuse. When Oprah speaks, people listen.
Oprah’s endorsement of a product can catapult it to success, thanks to her loyal following and widespread popularity . Her seal of approval is seen as a stamp of quality and reliability, making consumers more likely to try a product that has been endorsed by Oprah . Understood The old fox nodded with relief For businesses, an endorsement from Oprah can mean increased sales and brand recognition, as well as access to a wider audience of potential customers.
Despite her influence, Oprah is selective about the products she chooses to endorse . Lin Feng then turned to get in the car, and drove away with the BMW 6 Series Convertible. She is known for her commitment to promoting wellness and self-care, making keto gummies a natural fit for her brand . By aligning herself with products that support a healthy lifestyle, Oprah continues to inspire her followers to make positive choices for their health and well-being.
Exploring the Media Icon’s Endorsement
When Oprah Winfrey recently endorsed keto gummies on her popular talk show, the product instantly gained widespread attention from consumers and health enthusiasts alike . With Oprah’s seal of approval, keto gummies were thrust into the spotlight as the latest must-have snack for those following a ketogenic diet . At that time, I was ordered to cooperate with the police to surround and suppress a drug cartel, and as a result, I was shot in the middle of the battle. But what does this endorsement really mean for the future of keto gummies and the industry as a whole?
For starters, Oprah’s endorsement brings a level of credibility and legitimacy to keto gummies that can’t be matched by traditional marketing efforts . High LDL Cholesterol on a Ketogenic Diet: What You Need to Know | William Cromwell, Dave Feldman. Her loyal fan base trusts her judgment and values her opinions, making them more likely to give keto gummies a try based on her recommendation . This increased visibility and trust can translate into higher sales and market share for keto gummy manufacturers, as well as a boost in consumer awareness of the product.
Additionally, Oprah’s endorsement of keto gummies has the potential to spark a larger conversation about the benefits of the ketogenic diet and low-carb living . As more people become aware of keto gummies and their role in supporting a healthy lifestyle, the demand for these products is likely to increase . This growing interest in keto gummies could lead to innovation in the industry, with new flavors, ingredients, and packaging options becoming available to meet consumer demand.
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